antibiotic resistance

Infections of the urinary tract (UTI) are among the major causes of illnesses in hospitalized patients. UTI also the most common cause of illness among sexually active women in the community and patients with long-term indwelling urethral catheters. Urine specimens form the major part of the workload of the microbiology laboratory of the Eric Williams Medical Sciences Complex (EWMSC). Since the opening of the Microbiology Laboratory in 1991, the EWMSC, a 560-bed medical facility has isolated and reported the antibiotic sensitivities of a large number of urinary pathogens. The emphasis in the laboratory is on rapid turnaround time, accurate identification of isolates and reliable results. For this reason, many laboratories perform primary susceptibility testing to provide therapeutic guidance within 24 hours.

For many patients and doctors, however, this 24-hour delay is unacceptable and doctors must make empiric choices on treatment based upon local susceptibility patterns and patients’ clinical conditions. In other instances, particularly in rural communities in Trinidad, no microbiology laboratory testing is available to provide guidance, and in the absence of local sensitivity pattern and microbiology laboratory assistance, the initial choice of antibiotic therapy may descend to the level of emotional guesswork.

Accurate up-to-date record keeping of culture results and sensitivity patterns should be kept by laboratories and this information should be made available to policy formulators of the Ministry of Health. In Trinidad, documented baseline data on the scope of urinary pathogens are few or have not been updated. This is important because the demand for knowledge of sensitivity profiles of uropathogens is still crucial for successful antimicrobial therapy. canadian pharmacy viagra

The purpose of this study was to assess the changes in the spectrum of bacteria causing UTI and their susceptibility pattern, and to present an updated report from a previous study from this institution, to cover a continuous period of 10 years.